Label-free 4D-imaging of pathophysiological cell and tissue changes in precision-cut lung slices - Amsterdam 2025

Ex vivo modelling in lung research: new frontiers

Chair(s): Niki L. Reynaert, Antonella Dost

Session type: Poster session

Label-free 4D-imaging of pathophysiological cell and tissue changes in precision-cut lung slices

Naomi Esmee Duits

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Cell type-specific origins of oxidative/nitrosative stress drive the development of distinct COPD phenotypes

Stefan Hadzic

Abstract

Protective effects of a KEAP1 inhibitor in preclinical lung models of oxidative stress and cell damage

Karolina Öst

Poster

Abstract

LSC - 2025 - Investigating the mechanisms through which lung MSCs regulate endothelial functionality in COPD using distal lung organoid models

Mark Bell

Abstract

3D Lung Organoids as a Novel Model for Studying Ischemia-Reperfusion Injury in Lung Transplantation

Rosaria Tinnirello

Poster

Abstract

Ex Vivo Deposition and Pharmacokinetics of Inhaled RNA Therapeutics: Insights from the Isolated Perfused Rat Lung

Dorothee Winterberg

Poster

Abstract

WISP1 modulates inflammation and Oxidative Stress in COPD: evidence from a Lung-on-chip model

Maria Elpida Christopoulou

Poster

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Interleukin-21 exacerbates acute lung injury by increasing pulmonary microvascular endothelial permeability

Qiao Luo

Poster

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Pulmonary vascular leak: In vitro modelling of the microvasculature under flow conditions

Aoife Blake

Poster

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Cold storage of human Precision-Cut Lung Slices preserves cellular composition and transcriptional responses and enables on-demand translational lung research

Maria Camila Melo Narvaez

Poster

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Dynamic Pulmonary Aciniform Organoids for fibrosis modeling via mechanical expansion assessment

Satoshi Ikeo

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Small airways, big questions: how small airway disease relates to emphysema in COPD explant lungs

Thibo Verheyen

Poster

Abstract

The DDR1-TLN1 axis contributes to collagen synthesis in a chronic in vitro model of lung fibrogenesis.

Annabel Kunzemann Martinez

Poster

Abstract

Label-free 4D-imaging of pathophysiological cell and tissue changes in precision-cut lung slices

Naomi Esmee Duits

Poster

Abstract

Contributions from alveolar cell extrusion to cell-state transitions in lung fibrosis

Isabel Uwagboe

Poster

Abstract

A novel perfused muscle-on-chip platform to study muscle impairments in COPD

Sven Manse

Poster

Abstract

Attenuation of ventilation-induced endoplasmic reticulum stress associated with lung injury through phosphoinositide 3-kinase-? in a murine endotoxemia model

Li-fu Li

Abstract

Secretome profile of human alveolar epithelial type 2 cells from healthy and COPD subjects cultured in decellularised human lung slices

Anna-karin Larsson-callerfelt

Poster

Abstract

Late Breaking Abstract - Single-cell RNA sequencing reveals modified basal and club cells subtypes and accelerated aging in transplant recipients in an ex vivo airway epithelium model

Louise Bondeelle

Poster

Abstract

CDN Connection Issue

The ERS Congress 2025, Amsterdam

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